CCL7

CCL7
	nach PDB 1BO0
Andere Namen	Chemokine (C-C Motif) Ligand 7; Monocyte Chemoattractant Protein 3; SCYA7; MCP3; Small Inducible Cytokine A7 (Monocyte Chemotactic Protein 3); SCYA6; NC28; MARC; FIC;
	Vorhandene Strukturdaten: 1BO0, 1NCV
Eigenschaften des menschlichen Proteins
Masse/Länge Primärstruktur	99 Aminosäuren, 11200 Da
Bezeichner
Externe IDs	GeneCards: CCL7; OMIM: 158106; UniProt: P80098;

CCL7 (englisch CC-chemokine ligand 7) ist ein Zytokin aus der Familie der CC-Chemokine.

undefined

Eigenschaften

CCL7 ist an Entzündungsprozessen beteiligt.[1] Es wird von Monozyten und manchen Tumorzelllinien gebildet.[2] Die größte Homologie besitzen CCL7 und CCL2 (synonym MCP1). CCL7 bindet an die Matrix-Metalloprotease MMP2.[3]

Einzelnachweise

Opdenakker G, Fiten P, Nys G, Froyen G, Van Roy N, Speleman F, Laureys G, Van Damme J: The human MCP-3 gene (SCYA7): cloning, sequence analysis, and assignment to the C-C chemokine gene cluster on chromosome 17q11.2-q12. In: Genomics. 21, Nr. 2, 1994, S. 403–8. doi:10.1006/geno.1994.1283. PMID 7916328.
Opdenakker G, Froyen G, Fiten P, Proost P, Van Damme J: Human monocyte chemotactic protein-3 (MCP-3): molecular cloning of the cDNA and comparison with other chemokines. In: Biochem. Biophys. Res. Commun.. 191, Nr. 2, 1993, S. 535–42. doi:10.1006/bbrc.1993.1251. PMID 8461011.
G. A. McQuibban, J. H. Gong. E.M. Tam, C. A. McCulloch, I. Clark-Lewis, C. M. Overall: Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3. In: Science. 289, Nr. 5482, UNITED STATES, August 2000, S. 1202–6. doi:10.1126/science.289.5482.1202. PMID 10947989.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. The authors of the article are listed here. Additional terms may apply for the media files, click on images to show image meta data.

[pmid7916328-1] Opdenakker G, Fiten P, Nys G, Froyen G, Van Roy N, Speleman F, Laureys G, Van Damme J: The human MCP-3 gene (SCYA7): cloning, sequence analysis, and assignment to the C-C chemokine gene cluster on chromosome 17q11.2-q12. In: Genomics. 21, Nr. 2, 1994, S. 403–8. doi:10.1006/geno.1994.1283. PMID 7916328.

[pmid8461011-2] Opdenakker G, Froyen G, Fiten P, Proost P, Van Damme J: Human monocyte chemotactic protein-3 (MCP-3): molecular cloning of the cDNA and comparison with other chemokines. In: Biochem. Biophys. Res. Commun.. 191, Nr. 2, 1993, S. 535–42. doi:10.1006/bbrc.1993.1251. PMID 8461011.

[pmid10947989-3] G. A. McQuibban, J. H. Gong. E.M. Tam, C. A. McCulloch, I. Clark-Lewis, C. M. Overall: Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3. In: Science. 289, Nr. 5482, UNITED STATES, August 2000, S. 1202–6. doi:10.1126/science.289.5482.1202. PMID 10947989.