CCL26

CCL26
Andere Namen	Chemokine (C-C Motif) Ligand 26; Macrophage Inflammatory Protein 4-Alpha; Thymic Stroma Chemokine-1; CC Chemokine IMAC; Eotaxin-3; SCYA26; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 26; Chemokine N1; MIP-4-Alpha; TSC-1; IMAC;
	Vorhandene Strukturdaten: 1G2S, 1G2T
Eigenschaften des menschlichen Proteins
Masse/Länge Primärstruktur	94 Aminosäuren, 10648 Da
Bezeichner
Externe IDs	GeneCards: CCL26; OMIM: 604697; UniProt: Q9Y258;

CCL26 (englisch CC-chemokine ligand 26) ist ein Zytokin aus der Familie der CC-Chemokine.

Eigenschaften

CCL26 ist an Entzündungsprozessen beteiligt. Es wird im Herz, in der Lunge, in den Eierstöcken und in Interleukin-4-stimulierten Endothelzellen gebildet.[1][2] CCL26 bindet an den Rezeptor CCR3 auf Eosinophilen und Basophilen.[3]

Einzelnachweise

Shinkai et al. A novel human CC chemokine, eotaxin-3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinophils. J. Immunol. 163:1602-1610, 1999.
Guo et al. Molecular cloning and characterization of a novel human CC chemokine, SCYA26. Genomics 58:313-317, 1999.
Kitaura et al. Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3. J. Biol. Chem. 274:27975-27980, 1999.

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[1] Shinkai et al. A novel human CC chemokine, eotaxin-3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinophils. J. Immunol. 163:1602-1610, 1999.

[2] Guo et al. Molecular cloning and characterization of a novel human CC chemokine, SCYA26. Genomics 58:313-317, 1999.

[3] Kitaura et al. Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3. J. Biol. Chem. 274:27975-27980, 1999.