CCL21

CCL21
Andere Namen	Chemokine (C-C Motif) Ligand 21; SCYA21; SLC; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 21; Efficient Chemoattractant For Lymphocytes; Secondary Lymphoid Tissue Chemokine; Beta Chemokine Exodus-2; 6Ckine; CKb9; TCA4; ECL;
	Vorhandene Strukturdaten: 2L4N
Eigenschaften des menschlichen Proteins
Masse/Länge Primärstruktur	134 Aminosäuren, 14646 Da
Bezeichner
Externe IDs	GeneCards: CCL21; OMIM: 602737; UniProt: O00585;
	Orthologe

CCL21 (englisch CC-chemokine ligand 21) ist ein Zytokin aus der Familie der CC-Chemokine.

Eigenschaften

CCL21 ist an Entzündungsprozessen beteiligt. Es besitzt sechs statt der üblichen vier Cysteine.[1] CCL21 bindet an den Rezeptor CCR7.[2]

Einzelnachweise

Hedrick JA, Zlotnik A: Identification and characterization of a novel beta chemokine containing six conserved cysteines. In: J. Immunol.. 159, Nr. 4, 1997, S. 1589–93. PMID 9257816.
Yoshida R, Nagira M, Kitaura M, Imagawa N, Imai T, Yoshie O: Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7. In: J. Biol. Chem.. 273, Nr. 12, 1998, S. 7118–22. doi:10.1074/jbc.273.12.7118. PMID 9507024.

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[pmid9257816-1] Hedrick JA, Zlotnik A: Identification and characterization of a novel beta chemokine containing six conserved cysteines. In: J. Immunol.. 159, Nr. 4, 1997, S. 1589–93. PMID 9257816.

[pmid9507024-2] Yoshida R, Nagira M, Kitaura M, Imagawa N, Imai T, Yoshie O: Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7. In: J. Biol. Chem.. 273, Nr. 12, 1998, S. 7118–22. doi:10.1074/jbc.273.12.7118. PMID 9507024.